Clearing-factor lipase in obese–hyperglycaemic mice (ob/ob)
نویسندگان
چکیده
منابع مشابه
Clearing Factor, a Heparin-activated Lipoprotein Lipase
In the first paper of this series (l), evidence was presented which demonstrates that the clearing factor which appears in postheparin plasma is present in the hearts of normal, non-heparinized rats. This strongly supports the view that the enzyme functions in normal fat metabolism. In this paper, the substrate specificity of lipoprotein lipase is defined, the conversion of coconut oil into an ...
متن کاملAbsence of lipemia clearing factor lipase in human adipose tissue.
Lipoprotein lipase, or lipemia clearing factor lipase (which is more accurate terminology [l]) , is a heparin-activated enzyme which has been found in rat, beef, and pig heart (2). The adipose tissues of rats, rabbits, and especially chickens contain greater quantities of the enzyme (3). This latter observation led to the suggestion that the major site of lipoprotein lipase activity was in the ...
متن کاملThe inhibition in vivo of lipoprotein lipase (clearing-factor lipase) activity by triton WR-1339.
1. Lipoprotein lipase activity was measured in heart homogenates and in heparin-releasable and non-releasable fractions of isolated perfused rat hearts, after the intravenous injection of Triton WR-1339. 2. In homogenates of hearts from starved, rats, lipoprotein lipase activity was significantly inhibited (P less than 0.001) 2h after the injection of Triton. This inhibition was restricted excl...
متن کاملStability of lipoprotein lipase (clearing-factor lipase) in rat cardiac muscle [proceedings].
reticulum might suggest that addition of N-acetylglucosamine to the asparagine residue occurs while the nascent protein is associated with polyribosomes. But final conclusions must await information concerning the substrate specificity of UDP-N-acetylglucosamine-asparagine sequon N-acetyl-B-D-glucosaminyltransferase and its mechanism of action. The enzyme in the rough endoplasmic reticulum, bei...
متن کاملThe role of clearing-factor lipase (lipoprotein lipase) in the transport of plasma triglycerides.
The enzyme clearing-factor lipase, or lipoprotein lipase, is responsible for the removal of most of the plasma triglycerides from the bloodstream (Robinson, 1963). The main carriers of such triglycerides are the chylomicrons and the verylowdensity lipoproteins and these complexes are believed to be first sequestered by the enzyme at the lumen surfaces of the capillary endothelial cells of the e...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1972
ISSN: 0306-3283
DOI: 10.1042/bj1290447